Experimental neurology
Spatiotemporal multi-omics profiling of secondary brain injury after intracerebral hemorrhage in an optimized autologous blood-induced mouse model with human tissue validation.
Yang Du, Guangshuo Li, Yijun Lin, Zeqiang Ji, Yiwei Shi, Xiaojing Zhang, Na Zhou, Jia Zhang, Kaijiang Kang, Xingquan Zhao, Liheng Bian
Published: 202610.1016/j.expneurol.2026.115650
Abstract
BACKGROUND: Secondary brain injury (SBI) following intracerebral hemorrhage (ICH) involves complex molecular events such as oxidative stress, inflammation, and immune cell infiltration. Understanding their spatiotemporal patterns is essential for ide…
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