Experimental neurologyAnimalsMaleRatsSprague-DawleySignal Transduction
BMSC-EVs improve post-stroke cognition by promoting regionally distinct synaptic repair via Sema3G-Nrp2/PlexinA4 Signaling.
Yunsha Zhang, Xiaodan Bai, Penglin Yin, Yuying Guo, Liji Yang, Songlin Li, Xiaoxiao Zhao, Junjie Su, Aiqin Zhong, Linna Zhao, Shixin Xu
Published: 202610.1016/j.expneurol.2025.115563
Abstract
Cognitive impairment is a common sequela of ischemic stroke, primarily driven by disrupted synaptic structural plasticity in the hippocampus. Although bone marrow mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) are known to promote sy…
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