Experimental neurologyAnimalsAlzheimer DiseaseHyperbaric OxygenationMiceTransgenic
Hyperbaric oxygen therapy ameliorates Alzheimer's disease pathology by restoration of mitophagy and suppressing neuroinflammation in 5xFAD mice.
Min Yao, Zhuo Li, Yueling Lin, Hongbin Cai, Chang Sun, Lu Liu, Ying Long, Zhaoming Ge
Published: 202610.1016/j.expneurol.2025.115534
Abstract
Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) accumulation, synaptic dysfunction, and chronic neuroinflammation. Here, we demonstrate that hyperbaric oxygen therapy (HBOT) has multiple therapeutic effects in 5xFAD transgenic mice. HBOT…
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