Experimental neurologyAnimalsNitric OxideStreptozocinRatsMale
Modulation of the mediodorsal thalamic nitric oxide system ameliorated amnesia and medial prefrontal abnormal network activity in a streptozotocin-induced rat model of Alzheimer's disease.
Ali Yousefi, Farnaz Karimani, Ladan Delphi, Mohammad Rabiei Ghahfarokhi, Mohammad-Reza A Dehaqani, Ameneh Rezayof
Published: 202610.1016/j.expneurol.2025.115524
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by amnesia and neuronal network dysfunction. Given that the mediodorsal thalamus (MD) is connected to the medial prefrontal cortex (mPFC), and nitric oxide (NO) signal…
Preview only. Read the full abstract at the source