Experimental neurology
Bone marrow mesenchymal stem cell-derived exosomes alleviate neuropathic pain after spinal cord injury by inhibiting the TLR4/MyD88/NF-κB pathway.
Yuanzhi Xu, Shaoshuai Wang, Zefu Li, Junmin Wang, Menglu Wang, Qidi Xue, Jin Tao, Siyuan Huang, Yousef Rastegar-Kashkooli, Yusheng Xu, Xuemei Chen
Published: 202510.1016/j.expneurol.2025.115507
Abstract
BACKGROUND: Spinal cord injury-induced neuropathic pain (SCI-NP), characterized by complex pathophysiological mechanisms, represents a significant therapeutic challenge. Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) have demonstrated…
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