Experimental gerontology
Immune cell-associated DNA methylation responses to exercise in women: A bioinformatics analysis comparing pre- and postmenopausal stages.
Guilherme da Silva Rodrigues, Natalia Yumi Noronha, Andressa Crystine da Silva Sobrinho, Bernadette Jones-Freeman, Robin Grolaux, Camila Fernanda Cunha Brandao, Julio Sergio Marchini, Lígia Moriguchi Watanabe, Carla Barbosa Nonino, Andrew Teschendorff, Nir Eynon, Carlos Roberto Bueno Júnior, Macsue Jacques
Published: 202510.1016/j.exger.2025.112996
Abstract
INTRODUCTION: Menopause is associated with immunosenescence and altered immune profiles, potentially reducing immune competence. Physical exercise may counteract these changes by modulating DNA methylation in fitness-related genes. METHODS: This obse…
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