Experimental gerontologyAnimalsOxidative StressMaleRatsSprague-Dawley
The impact of hindlimb suspension on gastrointestinal integrity in aged rats: Segment-specific effects on inflammation and oxidative stress.
Ahmed Al-Dwairi, Sarah Obeidat, Aseel Shakhatreh, Othman Al-Shboul, Mohammad Alqudah, Mahmoud A Alfaqih, Doa'a G F Al-U'datt
Published: 202510.1016/j.exger.2025.112955
Abstract
BACKGROUND: Aging compromises gastrointestinal integrity and increases inflammation, making the elderly more vulnerable to physiological stressors. Prolonged immobility due to bedrest, frailty, or simulated microgravity, may exacerbate these age-rela…
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