Experimental gerontologyHumansFemaleOvarian NeoplasmsFibroblastsExtracellular Matrix
Impact of senescent fibroblasts secretome in ovarian cancer dissemination.
Luce Perié, Alexandra Landras, Mickaëla Bignard, Marion Theuret, Mélanie Briand, Franck Carreiras, Cédric R Picot
Published: 202510.1016/j.exger.2025.112909
Abstract
Aging is a significant risk factor in ovarian cancers, which remains one of the most lethal gynecological malignancies. Over 50 % of ovarian cancer cases occur in women aged 65 and older. During aging, senescent cells progressively accumulate in vari…
Preview only. Read the full abstract at the source