Experimental eye researchAnimalsAmyloid beta-PeptidesBlood-Retinal BarrierRatsPeptide Fragments
Role of P-glycoprotein in attenuation of retinal amyloid-β peptide (1-40) clearance across the rat inner blood-retinal barrier induced by lipopolysaccharide.
Kiyotaka Daikohara, Shin-Ichi Akanuma, Yuma Tega, Ken-Ichi Hosoya
Published: 202610.1016/j.exer.2025.110759
Abstract
In the retina, the accumulation of amyloid-β peptide (Aβ)(1-40) has been implicated in the development of inflammation-associated retinal diseases, highlighting the importance of understanding clearance mechanisms of retinal Aβ(1-40). This study aime…
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