Experimental eye researchHumansAqueous HumorGlaucomaProteomicsExtracellular Matrix
Extracellular matrix remodeling and endothelial fibrosis in Sturge-Weber syndrome secondary glaucoma: Insights from aqueous humor proteomics.
Lulu Huang, Minghan Wang, Mengyang Gu, Ning Wang, Chengrui Xu, Mengmeng Xu, Tongtong Yan, Yahan Ju, Dandan Zhang, Yue Wu, Hao Sun, Wenyi Guo
Published: 202610.1016/j.exer.2025.110753
Abstract
PURPOSE: Sturge‒Weber syndrome (SWS), a rare neurocutaneous disorder, frequently causes secondary glaucoma, leading to irreversible vision loss. The pathogenesis remains unclear, hindering targeted therapy development. This study investigated the mol…
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