Experimental eye researchAnimalsOptic DiskIntraocular PressureSwineSclera
Peripapillary scleral stiffening increases optic nerve head shear deformation in porcine eyes during IOP elevation.
Manqi Pan, Zihao Chen, Xueliang Pan, He Zhang, Matthew Reilly, Sayoko E Moroi, Jun Liu
Published: 202510.1016/j.exer.2025.110692
Abstract
Computational models predicted that peripapillary sclera (PPS) stiffening may reduce intraocular pressure (IOP) induced stresses and strains at the optic nerve head (ONH). Experimental studies in animal models of glaucoma however did not confirm such…
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