Experimental eye researchHumansEpitheliumCornealSirtuin 1NF-E2-Related Factor 2
Nitro Dihydrocapsaicin Attenuates Hyperosmotic Stress-Induced Inflammation in the Corneal Epithelial Cells via SIRT1/Nrf2/HO-1 Pathway.
Jatuporn Ngoenkam, Darawan Pejchang, Toenchit Nuamchit, Uthai Wichai, Sutatip Pongcharoen, Thanet Laorob, Pussadee Paensuwan
Published: 202510.1016/j.exer.2025.110680
Abstract
A hyperosmotic tear is a central pathogenic factor in dry eye disease (DED) that triggers inflammation, epithelial apoptosis, and structural damage to the corneal epithelium, accompanied by visual disturbances. The transient receptor potential vanill…
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