European urology
Primary Noncontrast Magnetic Resonance Imaging for Prostate Cancer Screening: A Randomized Clinical Trial (PROSA).
Emanuele Messina, Antonella Borrelli, Alessandro Sciarra, Ludovica Laschena, Debora Antonini, David Shaholli, Fabio M Magliocca, Simone Novelli, Daniele Santini, Giuseppe La Torre, Valeria Panebianco
Published: 202510.1016/j.eururo.2025.11.024
Abstract
BACKGROUND AND OBJECTIVE: Prostate-specific antigen (PSA)-based screening for prostate cancer (PCa) has limited accuracy, and it is linked to overdiagnosis. The PROSA trial aimed to evaluate whether a contrast-free biparametric magnetic resonance ima…
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