Epilepsy researchAnimalsEpilepsyTemporal LobeDisease ModelsAnimal
Allostatic load of immune cells in the spleen and brain of the Kcna1-null mouse model of temporal lobe epilepsy.
Jillian E Hinman, Ankita Aggarwal, Amberlee Haggerty, Stephanie A Matthews, Malavika Deodhar, Shruthi Iyer, Kristina A Simeone, Timothy A Simeone
Published: 202610.1016/j.eplepsyres.2025.107697
Abstract
Human temporal lobe epilepsy (TLE), particularly drug-resistant TLE, is associated with chronic peripheral immune activation. Here, we determined whether a similar association was detectable in a genetic mouse model of TLE with spontaneous recurrent…
Preview only. Read the full abstract at the source