Environmental pollution (Barking, Essex : 1987)
Increased S-adenosyl methionine strengthens the suppression in mitochondrial unfolded protein response induced by 6-PPD quinone at environmentally relevant concentrations in Caenorhabditis elegans.
Yuxing Wang, Guocheng Hu, Dayong Wang
Published: 202510.1016/j.envpol.2025.127231
Abstract
Exposure to 6-PPD quinone (6-PPDQ) caused mitochondrial dysfunction; however, underlying mechanisms remain largely unclear. In cells, S-adenosylmethionine (SAM) can be generated from methionine. In nematodes, 6-PPDQ (0.1-10 μg/L) reduced methionine c…
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