Environment international
Quantitative evaluation of genotoxicity data for risk assessment and regulatory decision-making: Time for a paradigm shift.
Benjamin Sachse, Sebastian Schmeisser, Jan van Benthem, Raffaella Corvi, Eugenia Dogliotti, Norman Ertych, Roland Frötschl, Ulrike Gündel, Kristin Herrmann, George Johnson, Carsten Kneuer, Jeannette König, Hans-Jörg Martus, Stefan Pfuhler, Stephanie Smith-Roe
Published: 202610.1016/j.envint.2026.110070
Abstract
Genotoxicity plays an important role in chemical safety assessment, as genetic alterations can lead to severe and irreversible health consequences. To date, the assessment of genotoxicity has mostly been limited to hazard identification, followed by…
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