European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Targeting the DKK1/CSF1 signaling axis to reprogram M2 macrophages and reverse chemoresistance in head and neck squamous cell carcinoma.
Chin-Sheng Huang, Chih-Ming Huang, Hang Huong Ling, Mao-Suan Huang, Ming-Shou Hsieh, Jia-Hong Chen
Published: 202610.1016/j.ejps.2026.107435
Abstract
BACKGROUND: Understanding the mechanisms underlying drug resistance in head and neck squamous cell carcinoma (HNSCC) is critical for the development of effective therapeutic strategies. M2-type tumor-associated macrophages (M2-TAMs), activated by col…
Preview only. Read the full abstract at the source