European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical SciencesNanoparticlesNebulizers and VaporizersLipidsHumansAdministration
Impact of formulation and process parameters on the stability and bioactivity of RNA-loaded lipid nanoparticles during nebulization.
Katrin F Wiebe, Stefan C Schneid, Werner Hoheisel, Wolfgang Frieß, Olivia M Merkel
Published: 202610.1016/j.ejps.2025.107383
Abstract
During the pandemic, lipid nanoparticles (LNPs) became widely established as RNA nanocarriers, and hold the promise of future targeting of a broad variety of previously untreatable diseases. LNPs are mostly administered invasively via intramuscular o…
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