European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical SciencesAdultAgedFemaleHumansMale
Evaluation of anti-drug antibodies against therapeutic monoclonal antibodies and related product in Japanese patients with rheumatoid arthritis and their clinical impact.
Hiroko Shibata, Kazuko Nishimura, Eri Tsukagoshi, Akiko Ishii-Watabe, Yoshiro Saito, Soichi Yamada, Shotaro Masuoka, Wataru Hirose, Shinichi Kawai, Toshihiro Nanki
Published: 202610.1016/j.ejps.2025.107357
Abstract
Biopharmaceuticals are widely used to treat rheumatoid arthritis (RA) due to their high therapeutic efficacy. However, these drugs may elicit immunogenicity and induce the production of anti-drug antibodies (ADA), potentially impacting their efficacy…
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