European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical SciencesCell-Penetrating PeptidesEndosomesHumansFluorescent DyesHeLa Cells
Monitoring endosomal escape of fluorescent cell-penetrating peptides.
Ali Hallaj, Gwenaël Labouèbe, Virginie Mansuy-Aubert, Evgeniya Trofimenko, Christian Widmann
Published: 202510.1016/j.ejps.2025.107330
Abstract
Cell-penetrating peptides (CPPs) have the capacity to transport cargos into cells either through endocytosis or direct translocation across the plasma membrane. CPPs entering via endocytosis remain generally trapped within endosomes and lysosomes. Th…
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