New hot-melt extruded drug/polymers for sustained delivery of hydrophilic S-propargyl-cysteine in rheumatoid arthritis.

Efficient embedding of highly hydrophilic drugs within poly (D, l-lactic-co-glycolic acid) (PLGA) to realize sustained release was substantially challenging. This study aimed to effectively embedding the hydrophilic low-molecular-weight compound S-pr…

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