European journal of pharmacology
Unraveling Sex-Related Cardiovascular Toxicity of Immune Checkpoint Inhibitors by Pharmacovigilance and Single-Cell Transcriptomic Analysis.
Shaocong Sang, Huiming Han, Mingyue Liu, Nan Zhang, Yanrui Cui, Kaidong Liu, Kai Xiong, Haihai Liang, Lifang Lv, Yunyan Gu
Published: 202610.1016/j.ejphar.2026.178569
Abstract
BACKGROUND: Immune-checkpoint-inhibitor (ICI) have revolutionized cancer treatment but can trigger severe immune-related adverse events (irAEs). Among these, cardiovascular irAEs (CV-irAEs) are rare yet associated with particularly high morbidity and…
Preview only. Read the full abstract at the source