European journal of pharmacology
Transglutaminase 2 activation is involved in thoracic aortic dissection through disruption of endothelial adherens junctions.
Xinyao Li, Weixin Zhang, Jie Gao, Lin Zhang, Yuqing Liao, Qin Liu, Qinghua Zhang, Chaoyun Wang, Lin Zhong, Xinkang Wang, Yumei Li
Published: 202610.1016/j.ejphar.2026.178548
Abstract
Thoracic aortic dissection (TAD) is a life-threatening condition. While medial degeneration is a hallmark of TAD, emerging evidence underscores endothelial dysfunction as a critical initiating event. However, the specific molecular mediators orchestr…
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