European journal of pharmacologyAnimalsOsteoblastsExtracellular MatrixProto-Oncogene Proteins c-aktMice
Maclurin promotes extracellular matrix formation in osteoblasts via PI3K/Akt pathway activation.
Ting Liu, Jiazhen Xu, Yujing Li, Bing Liang, Jiyixuan Li, Xiaobo Wen, Andy Lee, Ben Lam, Linyuan Xue, Dongming Xing
Published: 202610.1016/j.ejphar.2025.178504
Abstract
Mulberry (Morus nigra L.) is traditionally recognized for its bone-strengthening properties, yet its active constituents and underlying mechanisms remain incompletely understood. This study investigates the effects of maclurin, a key flavonoid from m…
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