European journal of pharmacologyAnimalsIschemic StrokePhosphatidylcholinesInterleukin-18Mice
Multi-omics analysis reveals the neuroprotective effects of phosphatidylcholine (18:1/18:2) on ischemic stroke by inhibiting plasma IL-18 levels.
Shengnan Wang, Xuying Xiang, Xiaoqing Guo, Mengting Qin, Jiaojiao Chen, Dailiang Jiang, Yuhang Feng, Yuhao Yuan, Ming Huang, Ling Mao
Published: 202610.1016/j.ejphar.2025.178444
Abstract
BACKGROUND: Observational studies show significant differences in plasma lipid profiles between ischemic stroke (IS) patients and healthy individuals, but the causal relationships are unclear. This study aimed to explore the causal links between 179…
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