Dual inhibition strategy in managing neuronal autophagy in PTZ-Induced kindling in mice: A pharmacological perspective on P2Y12 and SGLT2 inhibitors.

BACKGROUND: Epileptic seizures are closely related to imbalanced excitation and inhibition (E/I) of neurotransmission as well as dysregulation of autophagy, essential for maintaining neuronal homeostasis. Dapagliflozin and ticagrelor may attenuate ki…

Preview only. Read the full abstract at the source