European journal of pharmacologyAngiotensin IIFibrosisReceptorFibroblast Growth FactorType 1
Angiotensin II-induced fibrosis is mediated by activation of FGFR1 pathway in renal epithelial cells: Attenuation by chimeric peptide.
Jegadheeswari Venkadakrishnan, Audesh Bhat, Kirtikumar B Jadhav, Arti Dhar
Published: 202510.1016/j.ejphar.2025.178390
Abstract
Renal fibrosis is a prominent pathophysiologic change seen with the progression of chronic kidney disease. Angiotensin II (Ang II), the central peptide of the renin-angiotensin aldosterone system (RAAS), is known to cause fibrosis under various disea…
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