European journal of pharmacologyFlavanonesAnimalsCalcium ChannelsL-TypeVasodilation
Naringenin promotes coronary vasodilation via inhibition of L-type calcium channels (CaV1.2): Evidence from tissue bath and molecular studies.
Puneet Sharma, Pratishtha Sharma, Ashok Gaur, Kirti Purva, Ajay Bhati, Devendra Singh, Lakshmi Kant, Shivangi Gaur, Amit Kumar Pandey
Published: 202510.1016/j.ejphar.2025.178342
Abstract
Naringenin, a citrus-derived flavanone, was investigated for its vasorelaxant mechanisms in goat coronary arteries, focusing on endothelial signaling and direct inhibition of L-type calcium channels (CaV1.2). In silico docking against a homology-mode…
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