European journal of pharmacologyHumansAnimalsHydroxymethylglutaryl-CoA Reductase InhibitorsAntineoplastic AgentsCardiotoxicity
Statin-mediated protection in chemotherapy-induced intestinal and cardiac toxicity: current perspectives.
Nathalie Arendt, Maria Kopsida, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx
Published: 202510.1016/j.ejphar.2025.178282
Abstract
Chemotherapy-induced gastrointestinal and cardiac toxicities remain major dose-limiting complications of several cancer treatments, often leading to long-term morbidity and reduced quality of life. Increasing attention has been given to the pleiotrop…
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