European journal of pharmacologyAnimalsLipopolysaccharidesMiceHumansMale
OMT-28, a synthetic analog of 17,18-epoxyeicosatetraenoic acid, mitigates lipopolysaccharide-induced lung injury in mice.
Hironobu Tsubouchi, Rika Inomata, Shigehisa Yanagi, Moeka Honda, Katsuya Sakai, Anne Konkel, Janine Lossie, Wolf-Hagen Schunck, Masamitsu Nakazato, Taiga Miyazaki
Published: 202510.1016/j.ejphar.2025.178238
Abstract
Acute respiratory distress syndrome (ARDS) is a severe condition characterized by intense lung inflammation. Excessive oxidative stress and sustained inflammation in humans with ARDS compromise the epithelial barrier's integrity, leading to pulmonary…
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