European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.VAnimalsBenzodioxolesPiperidinesPolyunsaturated Alkamides2-Hydroxypropyl-beta-cyclodextrin
Development of piperine/HPβCD-loaded PVA-coated iron oxide nanoparticles in in situ gel for enhanced retinal delivery and anti-VEGF activity.
Phatsawee Jansook, Hay Man Saung Hnin Soe, Theingi Tun, Hay Marn Hnin, Supakarn Chamni, Rathapon Asasutjarit, Sarawut Lapmanee, Narumol Bhummaphan, Charoenchai Puttipanyalears, Sakkarin Bhubhanil, Anjaree Inchan, Natthawut Charoenphon, Yi Lu, Wei Wu
Published: 202610.1016/j.ejpb.2025.114931
Abstract
Piperine (PIP) is a potential therapeutic agent for retinal diseases; however, its poor aqueous solubility limits its ocular bioavailability. To overcome this limitation, a novel nanocarrier system was fabricated through the adsorption of PIP/hydroxy…
Preview only. Read the full abstract at the source