European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.VPolyvinyl AlcoholCryogelsDrug Delivery SystemsDiclofenacDrug Liberation
Poly(vinyl alcohol) cryogels: Effect size of polymer concentration, number of cycles and thawing rate on material properties and dermal drug delivery.
Y Wiedemann, T Schmitt, S Kim, K Dirnberger, S Ludwigs, D J Lunter
Published: 202510.1016/j.ejpb.2025.114876
Abstract
Poly(vinyl alcohol) (PVA) can be physically cross-linked by repeated freeze-thaw (F-T) cycles, resulting in a cryogel. Despite the growing prevalence of the cryogelation process in the scientific literature, its multivariable nature, particularly the…
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