European journal of medicinal chemistry
Construction and biological evaluation of novel carbazole-5-phenyl-1,3,4-oxadiazole derivatives as multi-target hypoglycemic agents.
Shuang Luo, Zhiyun Peng, Guangcheng Wang
Published: 202610.1016/j.ejmech.2026.118615
Abstract
To achieve new multi-target inhibitors simultaneously acting on α-glucosidase, α-amylase, and protein tyrosine phosphatase 1B (PTP1B), twenty-one novel carbazole-5-phenyl-1,3,4-oxadiazole derivatives (5a-5u) were synthesized and screened for in vitro…
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