European journal of medicinal chemistryXanthonesGlycoside Hydrolase InhibitorsAnimalsalpha-GlucosidasesTriazoles
Triazole-containing xanthone-furanose/pyranose hybrids: synthesis of potential α-glucosidase inhibitors.
Carlos D García-Mejía, Julio César Almanza-Pérez, Luis Fernando Cofas-Vargas, Abigail Aragón-Morales, Antonio Nieto-Camacho, Enrique García-Hernández, Eduardo Hernández-Vázquez
Published: 202610.1016/j.ejmech.2025.118384
Abstract
A collection of xanthone-carbohydrate hybrids is reported as potential α-glucosidase inhibitors. The inhibitory activity of the xanthone core and the poly-hydroxylated commercially available drugs inspired the design of the compounds. Accordingly, bo…
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