European journal of medicinal chemistryReceptorsCytoplasmic and NuclearHumansDrug DiscoveryAnimals
FXR-targeted drug discovery: Recent advances and therapeutic perspectives.
Qian Li, Zihang Liu, Weidong Shang, Xiangyang Zhou, Wu-Yu Mao, Yu Cao, Lianhai Shan
Published: 202610.1016/j.ejmech.2025.118332
Abstract
Farnesoid X Receptor (FXR), a pivotal member of the nuclear receptor superfamily, plays a central role in the regulation of crucial physiological processes. These processes encompass bile acid homeostasis, inflammatory responses, fibrosis, as well as…
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