European journal of medicinal chemistryHumansNAV1.8 Voltage-Gated Sodium ChannelDrug DiscoveryStructure-Activity RelationshipPain
Advances in the discovery of selective NaV1.8 inhibitors for pain management.
Zhixing Wu, Dai Lu
Published: 202610.1016/j.ejmech.2025.118326
Abstract
Pain management remains an unmet healthcare need, particularly in the development of effective non-opioid analgesics with improved safety profiles. Among emerging molecular targets, the voltage-gated sodium channel NaV1.8 has garnered significant att…
Preview only. Read the full abstract at the source