European journal of medicinal chemistryEpithelial-Mesenchymal TransitionHumansTriazolesColorectal Neoplasmsbeta Catenin
A novel 1,2,4-triazole derivative inhibits epithelial-mesenchymal transition in metastatic colorectal cancer via β-catenin suppression.
Heba Abdelmegeed, Heba Abo-Salem, Hayam A Abd El Salam, Eslam R El-Sawy
Published: 202610.1016/j.ejmech.2025.118279
Abstract
1,2,4-Triazole derivatives have emerged as a significant class of compounds with diverse biological activities, notably their anticancer properties. This therapeutic utility lies in their molecular flexibility and their capacity to interact with key…
Preview only. Read the full abstract at the source