European journal of medicinal chemistryHumansFerrous CompoundsMetallocenesCell ProliferationDihydrotestosterone
ROS-mediated antiproliferative effects of dihydrotestosterone-derived ferrocene-steroid conjugates toward human cancer cell lines of variable androgen dependence.
Vidak Raičević, Sandra Aranđelović, Nevenka Gligorijević, Biljana Dojčinović, Marko Rodić, André Stephan Ćulum, Niko Radulović
Published: 202610.1016/j.ejmech.2025.118276
Abstract
Ferrocene appendages often endow organic scaffolds with reactive-oxygen-species (ROS)-mediated cytotoxicity, yet ferrocene-androgen conjugates remain somewhat poorly explored, especially those linked at the steroid A-ring, known to modulate androgen…
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