European journal of medicinal chemistrybeta-LactamasesBacterial ProteinsHumansDrug DesignAnti-Bacterial Agents
Chemical probe design strategies to detect carbapenemase-producing organisms.
Foroogh Rezaei, Siu Wai Wong, Yue Qu, Nicolas H Voelcker, Manuela Jörg
Published: 202610.1016/j.ejmech.2025.118262
Abstract
β-Lactam antibiotics, including carbapenems, are vital for treating bacterial infections by inhibiting cell wall synthesis. As last-resort agents against multidrug-resistant (MDR) bacteria, carbapenems are increasingly compromised by the emergence of…
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