European journal of medicinal chemistryCarboplatinAspergillus fumigatusAnimalsDeferoxamineHumans
Repurposing carboplatin-based Pt(IV)-deferoxamine conjugates for infection theranostics.
Martin Kraihammer, Hristo P Varbanov, Kateřina Dvořáková Bendová, Miloš Petřík, Annie Yap, Giacomo Gariglio, Hubertus Haas, Clemens Decristoforo
Published: 202610.1016/j.ejmech.2025.118216
Abstract
Recently, multifunctional platinum(IV) complexes designed as prodrugs for the anticancer drug carboplatin and the iron chelator deferoxamine (DFO), each featuring a DFO unit at one axial position and either hemisuccinate or acetate at the other, were…
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