European journal of cell biologyHumansNeoplasmsAnimalsSignal TransductionProtein-Lysine 6-Oxidase
The role of the LOX family in cancer.
Diego Liviu Boaru, Diego De Leon-Oliva, Oscar Fraile-Martinez, Patricia De Castro-Martinez, Cielo Garcia-Montero, Connie Ferrara-Coppola, Majd N Michael Alhaddadin, Silvestra Barrena-Blázquez, Cristina De Las Peñas-González, Noemí Holgado-Tirado, Mónica Tordesillas-Vicente, Diego Torres-Carranza, Laura Lopez-Gonzalez, Raul Diaz-Pedrero, Melchor Alvarez-Mon
Published: 202610.1016/j.ejcb.2025.151527
Abstract
Lysyl oxidase (LOXs) are copper-dependent enzymes traditionally known for catalyzing the cross-linking of collagen and elastin, thereby ensuring extracellular matrix (ECM) stability. However, growing evidence reveals that their biological functions e…
Preview only. Read the full abstract at the source