European journal of cancer (Oxford, England : 1990)HumansNeoplasm StagingDNA Mismatch RepairMaleFemale
The impact of mismatch repair status on accuracy of clinical staging in stage II/III rectal cancer in daily practice.
Renee A Lunenberg, Ingrid A Franken, Manon N G J A Braat, Marloes A G Elferink, Frederieke H van der Baan, Miriam Koopman, Geraldine Vink, Martijn P W Intven, Femke P C Sijtsma, Jeanine M L Roodhart
Published: 202610.1016/j.ejca.2025.116117
Abstract
BACKGROUND: Accurate clinical staging of rectal cancer (RC) is critical for guiding neoadjuvant treatment decisions. In colon cancer, mismatch repair deficient (dMMR) tumours have shown a higher risk of overstaging, but the impact of mismatch repair…
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