European journal of cancer (Oxford, England : 1990)HumansColorectal NeoplasmsOrganoidsFemaleMale
Characterization of the cell-free DNA released by tumor organoids derived from colorectal cancer patients.
Alexia Mirandola, Jérôme Cartry, Sabrina Bedja, Ekaterina Pisareva, Corinne Prevostel, Céline Gongora, Benjamin Ginter, Antoine Italiano, Michel Ducreux, Alice Boilève, Jacques R R Mathieu, Fanny Jaulin, Alain R Thierry
Published: 202510.1016/j.ejca.2025.116097
Abstract
INTRODUCTION: Patient-derived tumor organoids (PDTOs) have histological, molecular and clinical (drug sensitivity) characteristics comparable to those of their originating tumors. However, little is known about their ability to replicate the release…
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