Integrated analysis of detoxification pathways and hepatotoxicity of butylated hydroxytoluene (BHT) in the Manila clam (Ruditapes philippinarum).

Synthetic phenolic antioxidants (SPAs) are emerging contaminants (ECs) of growing concern in marine ecosystems, yet their detoxification and hepatotoxicity in marine invertebrates remain largely unknown. Here, we integrated transcriptomic profiling,…

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