Ecotoxicology and environmental safetyParaquatSaccharomyces cerevisiaeOxidative StressHerbicidesVacuoles
Genomic variation in Saccharomyces cerevisiae influences paraquat response through differential oxidative stress and vacuolar adaptations.
Juan Carlos Rubilar, Benjamín Szenfeld, Francisco A Cubillos, Andrés D Klein
Published: 202510.1016/j.ecoenv.2025.119426
Abstract
The conserved genetics between Saccharomyces cerevisiae and mammals makes yeast an ideal model for studying the biological effects of paraquat (PQ), an herbicide linked to Parkinson's disease (PD) risk in humans. To determine how genetic background i…
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