Ecotoxicology and environmental safetyAnimalsZearalenoneRabbitsApoptosisAutophagy
SeMet attenuates zearalenone-induced autophagy in rabbit kidney to alleviate apoptosis through activation of PI3K/Akt/mTOR signaling pathway.
Qiongxia Lv, Wenjing Xu, Fan Yang, Jiahui Li, Wenjuan Wei, Xiaoguang Chen, Yumei Liu, Ziqiang Zhang
Published: 202510.1016/j.ecoenv.2025.119183
Abstract
Zearalenone (ZEA), a prevalent mycotoxin in moldy feeds, induces apoptosis by disrupting cellular homeostasis, leading to multi-organ damage, particularly in the kidneys, intestines, and reproductive system. Selenomethionine (SeMet), a natural amino…
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