Ecotoxicology and environmental safetyEpithelial-Mesenchymal TransitionSilicon DioxideExosomesAnimalsHumans
Mechanism of silica nanoparticles induced pulmonary epithelial-mesenchymal transition mediated by exosomal HNRNPAB.
Xiaoxu Zhao, Yujie Pan, Guanghao Yan, Yanan Yu, Yuguo Song
Published: 202510.1016/j.ecoenv.2025.119162
Abstract
BACKGROUND: Despite the widespread application of silica nanoparticles (SiNPs) and their known risk of pulmonary toxicity, their effects on lymphatic endothelial cells (LECs) and the mechanisms by which they promote pulmonary epithelial-mesenchymal t…
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