Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Acetylation-mediated fluconazole inactivation: A novel antifungal resistance mechanism.
Ludmila Gouveia-Eufrasio, Gustavo José Cota de Freitas, Danielle Letícia da Silva, Iara Rinco Silva, Daniel Santana de Carvalho, Milton T Drott, Bruna Carolina Teixeira Almeida, Cesar da Silva Santana Moura, Beatriz Murta Rezende Moraes Ribeiro, Maria Fernanda Liphaus Almeida Negreli, Lucas Cecilio Vilar, Silvia Maria Cordeiro Werneck, Grace Santos Tavares Avelar, Álan Natanael Pereira Gomes, Isabela Lima de Miranda
Published: 202610.1016/j.drup.2026.101359
Abstract
Antifungal resistance is considered a global health threat. However, enzymatic inactivation of antifungals, a common mechanism seen in antibacterial resistance, has not yet been described in fungi. From a One Health perspective, this study demonstrat…
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