Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Molecular profiling of chemotherapy-resistant breast cancer reveals DNA methylation remodeling associated with the acquisition of paclitaxel resistance.
Lenka Trnkova, Monika Burikova, Andrea Soltysova, Andrej Ficek, Jana Plava, Andrea Cumova, Lucia Rojikova, Kristina Jakic, Eva Sedlackova, Boris Tichy, Vojtech Bystry, Florence Busato, Yimin Shen, Miroslava Matuskova, Lucia Kucerova
Published: 202610.1016/j.drup.2026.101350
Abstract
AIMS: Chemotherapy resistance remains a major challenge in breast cancer (BC) treatment. This study aimed to investigate the role of DNA methylation in this complex process and evaluate the potential of the DNA methyltransferase inhibitor decitabine…
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