Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
The implied dysregulated RKIP-hypoxia axis in cancer and immune evasion: Clinical implications.
Ryan McWhorter, Salem Chouaib, Benjamin Bonavida
Published: 202510.1016/j.drup.2025.101328
Abstract
The Raf kinase inhibitor protein (RKIP) functions as both a metastasis suppressor and immune enhancer, exerting its influence over several key oncogenic signaling pathways, including the MAPK, NF-κB, and PI3K pathways. Recent studies have highlighted…
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